Opiant Pharmaceuticals Announces Publication of New Pre-Clinical Data Supporting Potential of OPNT005 as a Heroin Vaccine
Data Published Online in
The study describes an improved synthesis of a heroin-like molecule (a hapten) that is an essential component of OPNT005, which would make it practical to scale the synthesis of this molecule for clinical use. Additionally, OPNT005 produced high levels of antibodies in rodents. These antibodies cross react with heroin and other abused opioids, including oxycodone and hydrocodone. The pharmacological effects of intravenous heroin were significantly diminished in rodents receiving OPNT005.
“We are highly encouraged by these compelling pre-clinical results,” said
OPNT005 was developed jointly by the
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Source: Opiant Pharmaceuticals, Inc.